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Some sceptiscism is good, but remember to Posted by AdamB [Email] (#3) [Profile/Gallery] (more from AdamB) on Mon, 2 Aug 2004 16:14:17 In Reply to: Consider this viewpoint..., AlexP, Mon, 2 Aug 2004 10:37:09 Members do not see ads below this line. - Help Keep This Site Online - Signup |
be a bit critical of your sources. Using a website with the description "Wise Traditions in Food, Farming, and the Healing Arts", may not be the best place to find scientific knowledge. Using forum posts on an internet forum as any kind of evidence is dubious at best. Actually, the information in that article is extremely misleading. HMG-CoA reductase lowers *LDL*-cholesterol, but INCREASE HDL-cholesterol.
Only talking about total cholesterol shows a lack of understanding of the issue. LDL-cholesterol is the one associated with coronary disease, not necessarily total cholesterol. A high HDL-cholesterol is for example not associated with disease, quite the *opposite*. So you see it's the fractions of the different forms of cholesterol that is important.
Many REAL scientific studies have shown statins to reduce the risk of death caused by coronary heart disease *considerably*. The benefits hugely outweigh the risks associated with statins, when taken in proper doses and by people who have real cholesterol problems. Check out the Scandinavian Simvastatin Survival Study (the 4S-study). In the course of 5.4 years, it showed a 42% reduction in risk of death by coronary heart disease and a total reduction in risk of death by 30%. It involved 4444 patients. I can name several other huge studies showing the same kind of numbers, from all over the world.
Of course pharmacological treatment is for people who either don't respond to diet or who you can't get to diet, and like other drugs, statins shouldn't be used indiscriminately.
No doubt you can have some rare side effects (yes rhabdomyolysis *is* rare), as with any other drug, but to talk about it being useless because it is overprescribed is not rational. As someone said earlier in the thread, there are people who are genetically predisposed to extremely high levels of LDL and free cholesterol, and who are definitely more at risk for coronary heart disease than others. To suggest they shouldn't take statins is very bad advice.
It's natural for people to want to figure stuff out for themselves, but it's rather arrogant to think you understand everything there is to know about heart medicine, just because you've done some research on the internet, which is ripe with disinformation, hidden agendas and outright lies. Read a textbook on internal medicine and a pharmacology book instead, if you want some scientific information instead of anecdotes.
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